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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '295e04db3038d5187fa237a221daf26c6251635af007f8b8e21d4738e60d088f' 
  AND token = 'lo9VmQWmee2XB3H+bW/ru4VqhcuAykua6VfpyWE5At8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}