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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd61adb2e1f6f4adcb8a1da67d85b9a3d3864b456109ac645f74e8be8b20822a' 
  AND token = 'OCSVmL9GaX5JAmnEWNnrJJUjbRyOulPfDbwf9Q1OnWA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}