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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '69721f14acdf3cfb1e683461d919b347d0be59bdc33df9879e73f0f1e70e4b78' 
  AND token = 'WjktvLEQvH1o2JAwrvZGPyXIgQ0oZJ1X1Vlu0VQv7Sk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}