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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f51909d5ce10246dd4ff0efdb868847e9a6411a9f1e2595681e6d996cd400c0b' 
  AND token = 'AfLBYuG649f5Zw4/TjeZFpHAsC3Uk0YplyLrQNmXjQI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}