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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd68b345245c780449c443de5d71b48b287049f1b57bb2c932e3e6d48f607a25a' 
  AND token = '+SIK9xahPvq16L682zdW9YzsxLIusLI4mOFUC+kVE40=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}