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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67b81215756e4b938626d8dd42e419df1eb6a80d2144901f5694286a2eef2a70' 
  AND token = 'VwWqhhNl+j9m+W1i291BWvr1ygxkdaO7II+7CQUgsqI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}