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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '601b1d1a937a195c4e0f1e6dbd330dee0496aa0e199aff9d3148a26a144fa9b7' 
  AND token = 'kD/VJXcGCf9c2XPmDSpTfF3C+/YDdMtWKI7lpGQu66M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}