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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8648100f8633cbc802ba59594165794fb8426fee6caed97edfa27e61e0083815' 
  AND token = 'M+uO2wkGufkCLFgUTcVvCOn4Cfg/letfMwAHaqfjoiQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}