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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4965ed3cd96bb7e4826d575107564967b246d9b0bc2c4360c9e88ebfe2e34f9d' 
  AND token = 'TWvyEs9j7ccx5mvgHT3aIrtf7e0pJWrRmBPNF44uPlw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}