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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a4686111d655eba2b98358f8a76611d46cb6df1f605d7dcb3c1fd6ec307bb20' 
  AND token = 'pTLni81+yOD4TW8rrpiY1u5UlgI8oTxx1bXHzr+vdYI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}