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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8a977782be6eaf9287a0b8cfa49ad04895103c8aad94f1f75e7073500145fe7' 
  AND token = '0iXQ+hIqbER6xuPeWSKieUjTtRWjPDqOJGZH9nc46WY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}