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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d42e3c2de44acc9567b2e242c396b0e7da903cf22022d3c247d777748f45266' 
  AND token = '7ZoX6yUS0L3V/Yi9/yjKj1XjYu25+FDJ/UCEACPg/AY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}