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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd458f7d8e38dea82f9a86f94696f308953b7e7c4b5cf9eabb71f3180f6ce4ff0' 
  AND token = 'CArCIFfXEFu6dA189wk+L5JJ+XehmE8l0D4ZVJRJiR8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}