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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '223888cf0d6e888dadde8d1b41d24a2ca75ed4731f3188cc77b7344d4e268c09' 
  AND token = 'kjXXSyQS5aLvB4ZtJL1CbSNSKyu3QqO4JvJN1uexz7I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}