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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46dbd9808c4330069f5c4e67145b0c9ec0a200f314e7d96e557826f742dd45af' 
  AND token = '25AWTdVK7mKTsSEGMRhNOtuAcaN4H/M8SRv+V1gn2sU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}