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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bb214f4a9b50c8f1d0445208baaba5cf7e65483db4ff95c893650faa2b0fb045' 
  AND token = 'c3xQ2IXQ7/lNdWBQrLttS2zM54wXpAJtz+EsVRNbWJ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}