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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a166d68036c8d290d7a610d627c3c719b6e8ff9fd62e82f4385f987398cd084e' 
  AND token = 'e2KYVazag3YnjWB8aYny/PwMM4zxELpFaSonmJMjDcQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}