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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e409c8a5c5328b0c78a329975a5f98b0c55ab6d214546f928fd491e8c92d3304' 
  AND token = 'fTH+NLqo7n50R1/0rIS9TDFP7wbpK0tMI2QIcXM8HkY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}