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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0e2fb3f9d1c060246d57b8eafbe04ade1bf7645654b93493c596bb5542a62f7' 
  AND token = 'ZZhbSVO2sY925H/iXTmA704I7qKcwBf4waczZ25FEI0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}