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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4fdf1233bb66019d80160d57173525365fe9e350d2dea9fd07bd779a0bcaa36e' 
  AND token = 'P9KhcLdKdlKPQhRh6iJo4fpN+uWZ4upZAcY/wRZXM7w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}