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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1635136c534d6345a95c40e25887add9c16e6158e4f83008a069d47a0cc5db1' 
  AND token = 'TwD7bSDEk8EiSDFcV3KNHLzQbHGQ9CbnCSv/Necb9ms=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}