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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8d6e61fcf1ade6aacfd360655808d426b9c5c5b971a522ea60009a65b9a9293' 
  AND token = '+rZTXdSBlrKDim9S8oTd9l1HLPISiwRRqDYke27zrG0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}