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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b0cb1db868e05e706f3df6cc3c84281e3c63c7cc8b6b31fc5446859a7d6954a' 
  AND token = '3JnCe9JnCv0l7/PTLPS2CBzIleIe99/n6OHlhyAsVSw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}