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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2aed5c39e08251c6ca0dfd18e5a897bd6cf94c31092dcae8834f9df07989d46f' 
  AND token = 'X7oAA3b/fo1Q+YwhnfrefxMM2vJ88Q78HYc/kvyJ0OE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}