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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f1395070b43c02e0cf9be90d7f6329cae801f428acd528163a8d04256c30f5a' 
  AND token = 'rpBlnsQrqE9cGH/TCCkkdKy1vquN5BWnyqNruwuRcWg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}