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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3cacea3ea02952b7872870cd974e28b3e52ef8178f68deb44928e3348f126fac' 
  AND token = 'K6RBGnyiIue8xAxm/WPUd2rx7DBRr5Rjy/KDOtnuFbE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}