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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14114aa1f5bf5e7024fffb769b45a05c15a2a89e46602351a5dd110ac20de7a3' 
  AND token = 'o9So25YUNmVQ0Tm8WpTReHLuYJuX8nMnCcBwN51L2+s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}