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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fcf2a6fb9c278296244da5258f3daba72deb80f6318c7615ba2d7d94749c9c70' 
  AND token = '+6LLkA1hxor4Io0Sza+9LzuOCxWxmiF8Wa7jOIdDjjs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}