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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59611aafc839b4310a5589ed599772826fa2b7ccfb5494a2f370ef388ee5a1c5' 
  AND token = 'gP6Ra+XVN4pab6wNxWCXij7GBhGNt3iAeWCm5PXMntQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}