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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c111402ed16a1c582ed7414a9adb6fe4411a4396a101e2f3783b54697c06b8cb' 
  AND token = 'A7MPDPF7PuJfZx6vMsawzFvYwA49+dtBJql0IV7a69Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}