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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b2cf323e7d47fe40a60c1740e3cf0c315cd309842ea0b2643df64c779444b9d' 
  AND token = 'kB254p/7iwPEVUZUMeqVypRPh+/O3BS2au1b6Bjb+vQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}