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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3cefcdba17435106996b61d7aaa3936b8ff96c91c1c39e851a16da7760d2dc68' 
  AND token = 'EN6pjcBzGhOPb3bOROPj6W5xcUMKOLkz4UQaY+LjgZ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}