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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '037c4af16c150153cd1d1c321250c6084b867863b79b97246a80ff7c8dd5136c' 
  AND token = 'H6yWbBAerEAmMXdZtNO5CfRTyknWMcB3pmrPz+F6Jp0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}