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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '89d51510a206fb6cab32641b1be677a9655b6e8842f58fcbe9a2e68960ebb2b6' 
  AND token = 's2uWdgKJkp4iebhJAeLcb9JWCCI8AbKY9ZvlFBySRT4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}