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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0fed08ac2f2ae26f56cf562ccaf3d23ab40f34f3320e9aa53626e2a4ea00e49' 
  AND token = 'BEHVZUSsCRx2kSBd/LC5f64pMwWLj0+dib+mHSEVAkM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}