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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3980e7f8a03938c04c98a44736e0bfada730fe9c506a70c43c5c57f60fb218dd' 
  AND token = '7bc+aUHA0684IcxCTcd5XRBdJJJZf9IWxeC42qNLiO4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}