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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2dc599e19dfcec6224ba91308daf7423592426c3992328b4ef7401cade2d49e1' 
  AND token = 'QeKccD+kThBsQKW3JtTFecAOk0gg7kUaVhTpbtkaPdU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}