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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e70665d8368d9ee6b8c6c94720c3735bcf3fb68d46fb7d873c3d888541536c3' 
  AND token = 'GV9wRTGfPqjnt9nqAppeJdi8x+ZCsRHkgshdzhbkf9g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}