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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '824a1af14d5c07c771687bc4f1c06d5562a6f41fb476222135116d631ca0d0a6' 
  AND token = 'mTNHsAG6BAbKpJLjYwXVlj3UIdBx0lV57m5wSd+VSGA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}