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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72807176caccc1bd96e2273a8c29417ee08c160d2d99f867813796c866971eb3' 
  AND token = 'KBDM21AXM2XJC3X3vFxRBbINNtRe/s9i/mZE8cu3Efc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}