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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '859c52af51076308c8a46701066481405e012aaa83e6483a12d0ccaffbe6f3b1' 
  AND token = 'KLOP8oS/pTdiHSYq45IKO9hCBWuYuTp6ZRHUW2gfRJQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}