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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc76dc91c9bc545098ad6f322fba3835b8a218d32529abac122545e5755dffba' 
  AND token = 'hxcjy1GJ9JVNWEEMdW2P1mh2H4E8uJa3B0m6ylqDleI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}