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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9607a4417064fa11e1fda6f4b22c0170c62c883d1015e2a4f6427f71e977dd02' 
  AND token = 'kIi2KIrXmBuTgZlKNMcPWUh8CF2B7uUbITasgxN3zpA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}