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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5efdd1bce75613a622a5ab6af2e5329aa4a7a2635a3ab75be8e98c493fa76600' 
  AND token = 'Rx8YOqthdeSDLucKpwHMBvMle94g8FAdRPeBeSbZXcc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}