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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b5697e9df4fb1f0527a8cf1113711272776b25a69a5e76526d534a5c8e8dab0' 
  AND token = 'I9dLSYfFI9639Oz12Y+ALPy+ocRXk/3/uRB1IlhIKGM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}