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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e6d9609d3e41265704e1a4a1fc8bcc7d81047d0bf6f44e44d9976efd8fa8967' 
  AND token = 'WEGR7qSJmtOpWcjJ/UJ41hSCFpX2eEzXVlw1+buEf9M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}