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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd13a3381988809222697618e7759c5c7f4c9f0e7dfdb359e51ab06c0a2014bb9' 
  AND token = 'yuvrmR00c+SERf4lZR3+lmswW0Tzt6KqETNeQ2Lxdnw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}