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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0a0cfd190c9094fd946416cdf81b911ba4ac848d52716a8a6d99c39c42972b5' 
  AND token = 'qVF8s+AWWME7wu/aU044rL6v8CFFi1tuVk+mb1yk5kU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}