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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c555f8471bd1b29cae981b9d718bef4597bd47efc46c59f15d4fc020b05512a2' 
  AND token = 'xoMVN1hnqSlnu+fgAwHe0Dny0mom7gMXMz3rtHVj6yY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}