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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42a0acaa37241d6186ffe7343e8c1f13cb231e396d98a4bc3eb9814b52d09ca8' 
  AND token = 'THucpaI+IcUEKRjC8lHhTHMtdFVPsSQaHxcyJAG0dkQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}